Serum glutamate pyruvate transaminase (SGPT) levels and histopathological of KUB chicken liver given water extract of neem leaves (Azadirachta indica) in drinking water

Azadirachta indica A. Juss or neem is herbal that contains antioxidants and bioactive compounds of alkaloids, steroids, flavonoids, saponins tannins can play a role in various biological activities. The purpose this study was to determine the effect water extract leaves mixed drinking on liver health performance KUB chickens. observed variables were serum glutamate pyruvate transaminase (SGPT) levels histopathology. experimental animals used chickens (Kampung Unggul Balitbangtan), using Completely Randomized Design (CRD) with four treatments five replications. treatment group consisted P0 (control 0%), leaf 1% (P1), 3% (P2) 5% (P3) administered during starter phase (42 days). 200 tails. Preparation histology preparations by paraffin method. SGPT tested IFCC2 Enzymatic Kinetic method (International Federation Clinical Chemistry Laboratory Medicine). results showed chicken not significantly different between control treatment. Liver data inflammatory cell infiltration damage, degeneration, necrosis, vessel congestion but there no significant difference livers. Water supplementation has negative